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Doxycycline Delays Aneurysm Rupture in a Mouse Model of Marfan Syndrome
OBJECTIVES: Thoracic aneurysms are the main cardiovascular complication of Marfan syndrome (MFS) resulting in premature death. MFS has been associated with mutations of the gene encoding fibrillin-1 (FBN1), a major constituent of the elastic fibers. Matrix metalloproteinases (MMPs) are important in...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4148046/ https://ncbi.nlm.nih.gov/pubmed/18178469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jvs.2007.09.016 |
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