Knockout Mice Reveal Key Roles for Claudin 18 in Alveolar Barrier Properties and Fluid Homeostasis

Claudin proteins are major constituents of epithelial and endothelial tight junctions (TJs) that regulate paracellular permeability to ions and solutes. Claudin 18, a member of the large claudin family, is highly expressed in lung alveolar epithelium. To elucidate the role of claudin 18 in alveolar...

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Detalhes bibliográficos
Main Authors: Li, Guanglei, Flodby, Per, Luo, Jiao, Kage, Hidenori, Sipos, Arnold, Gao, Danping, Ji, Yanbin, Beard, LaMonta L., Marconett, Crystal N., DeMaio, Lucas, Kim, Yong Ho, Kim, Kwang-Jin, Laird-Offringa, Ite A., Minoo, Parviz, Liebler, Janice M., Zhou, Beiyun, Crandall, Edward D., Borok, Zea
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2014
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148039/
https://ncbi.nlm.nih.gov/pubmed/24588076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2013-0353OC
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