Knockout Mice Reveal a Major Role for Alveolar Epithelial Type I Cells in Alveolar Fluid Clearance

Active ion transport by basolateral Na-K-ATPase (Na pump) creates an Na(+) gradient that drives fluid absorption across lung alveolar epithelium. The α1 and β1 subunits are the most highly expressed Na pump subunits in alveolar epithelial cells (AEC). The specific contribution of the β1 subunit and...

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Detalles Bibliográficos
Publicado en:Am J Respir Cell Mol Biol
Main Authors: Flodby, Per, Kim, Yong Ho, Beard, LaMonta L., Gao, Danping, Ji, Yanbin, Kage, Hidenori, Liebler, Janice M., Minoo, Parviz, Kim, Kwang-Jin, Borok, Zea, Crandall, Edward D.
Formato: Artigo
Idioma:Inglês
Publicado: American Thoracic Society 2016
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5023030/
https://ncbi.nlm.nih.gov/pubmed/27064541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2016-0005OC
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