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OncodriveROLE classifies cancer driver genes in loss of function and activating mode of action

Motivation: Several computational methods have been developed to identify cancer drivers genes—genes responsible for cancer development upon specific alterations. These alterations can cause the loss of function (LoF) of the gene product, for instance, in tumor suppressors, or increase or change its...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Schroeder, Michael P., Rubio-Perez, Carlota, Tamborero, David, Gonzalez-Perez, Abel, Lopez-Bigas, Nuria
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147920/
https://ncbi.nlm.nih.gov/pubmed/25161246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu467
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