Bioinformatics-driven discovery of rational combination for overcoming EGFR-mutant lung cancer resistance to EGFR therapy

Motivation: Non–small-cell lung cancer (NSCLC) is the leading cause of cancer death in the United States. Targeted tyrosine kinase inhibitors (TKIs) directed against the epidermal growth factor receptor (EGFR) have been widely and successfully used in treating NSCLC patients with activating EGFR mut...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kim, Jihye, Vasu, Vihas T., Mishra, Rangnath, Singleton, Katherine R., Yoo, Minjae, Leach, Sonia M., Farias-Hesson, Eveline, Mason, Robert J., Kang, Jaewoo, Ramamoorthy, Preveen, Kern, Jeffrey A., Heasley, Lynn E., Finigan, James H., Tan, Aik Choon
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2014
Gaiak:
Discovery Note
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147888/
https://ncbi.nlm.nih.gov/pubmed/24812339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu323
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