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Metformin directly acts on mitochondria to alter cellular bioenergetics

BACKGROUND: Metformin is widely used in the treatment of diabetes, and there is interest in ‘repurposing’ the drug for cancer prevention or treatment. However, the mechanism underlying the metabolic effects of metformin remains poorly understood. METHODS: We performed respirometry and stable isotope...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Andrzejewski, Sylvia, Gravel, Simon-Pierre, Pollak, Michael, St-Pierre, Julie
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147388/
https://ncbi.nlm.nih.gov/pubmed/25184038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2049-3002-2-12
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