XIAP inhibitors induce differentiation and impair clonogenic capacity of acute myeloid leukemia stem cells

Acute myeloid leukemia (AML) is a neoplasia characterized by the rapid expansion of immature myeloid blasts in the bone marrow, and marked by poor prognosis and frequent relapse. As such, new therapeutic approaches are required for remission induction and prevention of relapse. Due to the higher che...

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Autori principali: Moreno-Martínez, Daniel, Nomdedeu, Meritxell, Lara-Castillo, María Carmen, Etxabe, Amaia, Pratcorona, Marta, Tesi, Niccolò, Díaz-Beyá, Marina, Rozman, María, Montserrat, Emili, Urbano-Ispizua, Álvaro, Esteve, Jordi, Risueño, Ruth M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2014
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147327/
https://ncbi.nlm.nih.gov/pubmed/24952669
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