XIAP inhibitors induce differentiation and impair clonogenic capacity of acute myeloid leukemia stem cells

Acute myeloid leukemia (AML) is a neoplasia characterized by the rapid expansion of immature myeloid blasts in the bone marrow, and marked by poor prognosis and frequent relapse. As such, new therapeutic approaches are required for remission induction and prevention of relapse. Due to the higher che...

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Detalhes bibliográficos
Main Authors: Moreno-Martínez, Daniel, Nomdedeu, Meritxell, Lara-Castillo, María Carmen, Etxabe, Amaia, Pratcorona, Marta, Tesi, Niccolò, Díaz-Beyá, Marina, Rozman, María, Montserrat, Emili, Urbano-Ispizua, Álvaro, Esteve, Jordi, Risueño, Ruth M.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147327/
https://ncbi.nlm.nih.gov/pubmed/24952669
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