The lincRNA HOTAIRM1, located in the HOXA genomic region, is expressed in acute myeloid leukemia, impacts prognosis in patients in the intermediate-risk cytogenetic category, and is associated with a distinctive microRNA signature

Long non-coding RNAs (lncRNAs) are deregulated in several tumors, although their role in acute myeloid leukemia (AML) is mostly unknown. We have examined the expression of the lncRNA HOX antisense intergenic RNA myeloid 1 (HOTAIRM1) in 241 AML patients. We have correlated HOTAIRM1 expression with a...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Díaz-Beyá, Marina, Brunet, Salut, Nomdedéu, Josep, Pratcorona, Marta, Cordeiro, Anna, Gallardo, David, Escoda, Lourdes, Tormo, Mar, Heras, Inmaculada, Ribera, Josep Maria, Duarte, Rafael, de Llano, María Paz Queipo, Bargay, Joan, Sampol, Antonia, Nomdedeu, Mertixell, Risueño, Ruth M., Hoyos, Montserrat, Sierra, Jorge, Monzo, Mariano, Navarro, Alfons, Esteve, Jordi
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2015
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741628/
https://ncbi.nlm.nih.gov/pubmed/26436590
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