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Predicting when Biliary Excretion of Parent Drug is a Major Route of Elimination in Humans

Biliary excretion is an important route of elimination for many drugs, yet measuring the extent of biliary elimination is difficult, invasive, and variable. Biliary elimination has been quantified for few drugs with a limited number of subjects, who are often diseased patients. An accurate predictio...

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Detalhes bibliográficos
Main Authors: Hosey, Chelsea M., Broccatelli, Fabio, Benet, Leslie Z.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4147063/
https://ncbi.nlm.nih.gov/pubmed/25004821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-014-9636-1
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