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RhoA and RhoC -siRNA inhibit the proliferation and invasiveness activity of human gastric carcinoma by Rho/PI3K/Akt pathway

AIM: To evaluate the effects of adenovirus-mediated gene transfer of RhoA siRNA and RhoC siRNA on proliferation and invasion of SGC7901 cells by Rho/ PI3K/Akt pathway. METHODS: Plasmid of RhoA siRNA and RhoC siRNA were constructed and transfected into SGC7901 cells. siRNA and LY294002 (PI3K inhibito...

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Detalhes bibliográficos
Main Authors: Sun, Hua-Wen, Tong, Shi-Lun, He, Jie, Wang, Qi, Zou, Li, Ma, Shu-Jing, Tan, Hai-Yan, Luo, Jian-Fei, Wu, Hong-Xue
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146790/
https://ncbi.nlm.nih.gov/pubmed/17659701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v13.i25.3517
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