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Impact of Recurrent Copy Number Alterations and Cancer Gene Mutations on the Predictive Accuracy of Prognostic Models in Clear Cell Renal Cell Carcinoma

PURPOSE: Several recently reported recurrent genomic alterations in clear cell renal cell carcinoma (ccRCC) are linked to pathological and clinical outcomes. We determined if any of the recurrent cancer gene mutations or copy number alterations identified in the Cancer Genome Atlas (TCGA) ccRCC data...

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Detalhes bibliográficos
Main Authors: Hakimi, A Ari, Mano, Roy, Ciriello, Giovanni, Gonen, Mithat, Mikkilineni, Nina, Sfakianos, John P, Kim, Philip H, Motzer, Robert J, Russo, Paul, Reuter, Victor E, Hsieh, James J, Ostrovnaya, Irina
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146751/
https://ncbi.nlm.nih.gov/pubmed/24518768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.juro.2014.01.088
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