Neutrophil extracellular trap-derived enzymes oxidize high-density lipoprotein: an additional proatherogenic mechanism in systemic lupus erythematosus

OBJECTIVE: Oxidative stress and oxidized high-density lipoprotein (oxHDL) are implicated as risk factors for cardiovascular disease (CVD) in systemic lupus erythematosus (SLE). Yet, how HDL is oxidized and rendered dysfunctional in SLE remains unclear. Neutrophil extracellular traps (NETs), which ar...

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Main Authors: Smith, Carolyne K., Vivekanandan-Giri, Anuradha, Tang, Chongren, Knight, Jason S., Mathew, Anna, Padilla, Robin L., Gillespie, Brenda W, Carmona-Rivera, Carmelo, Liu, Xiaodan, Subramanian, Venkataraman, Hasni, Sarfaraz, Thompson, Paul R., Heinecke, Jay W., Saran, Rajiv, Pennathur, Subramaniam, Kaplan, Mariana J.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146708/
https://ncbi.nlm.nih.gov/pubmed/24838349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38703
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