Lupus high-density lipoprotein induces pro-inflammatory responses in macrophages by binding lectin-like oxidized low-density lipoprotein receptor-1 and failing to promote activating transcription factor 3 activity

OBJECTIVES-: Recent evidence indicates that high-density lipoprotein (HDL) exerts vasculoprotective activities by promoting activating transcription factor 3 (ATF3), leading to down-regulation of TLR-induced inflammatory responses. Systemic lupus erythematosus (SLE) is associated with increased card...

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Detalhes bibliográficos
Publicado no:Ann Rheum Dis
Main Authors: Smith, Carolyne K., Seto, Nickie L., Vivekanandan-Giri, Anuradha, Yuan, Wenmin, Playford, Martin P., Manna, Zerai, Hasni, Sarfaraz A., Kuai, Rui, Mehta, Nehal N., Schwendeman, Anna, Pennathur, Subramaniam, Kaplan, Mariana J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6109980/
https://ncbi.nlm.nih.gov/pubmed/27543414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2016-209683
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