Neutrophil extracellular trap-derived enzymes oxidize high-density lipoprotein: an additional proatherogenic mechanism in systemic lupus erythematosus

OBJECTIVE: Oxidative stress and oxidized high-density lipoprotein (oxHDL) are implicated as risk factors for cardiovascular disease (CVD) in systemic lupus erythematosus (SLE). Yet, how HDL is oxidized and rendered dysfunctional in SLE remains unclear. Neutrophil extracellular traps (NETs), which ar...

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Autors principals: Smith, Carolyne K., Vivekanandan-Giri, Anuradha, Tang, Chongren, Knight, Jason S., Mathew, Anna, Padilla, Robin L., Gillespie, Brenda W, Carmona-Rivera, Carmelo, Liu, Xiaodan, Subramanian, Venkataraman, Hasni, Sarfaraz, Thompson, Paul R., Heinecke, Jay W., Saran, Rajiv, Pennathur, Subramaniam, Kaplan, Mariana J.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146708/
https://ncbi.nlm.nih.gov/pubmed/24838349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38703
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