Neutrophil extracellular trap-derived enzymes oxidize high-density lipoprotein: an additional proatherogenic mechanism in systemic lupus erythematosus

OBJECTIVE: Oxidative stress and oxidized high-density lipoprotein (oxHDL) are implicated as risk factors for cardiovascular disease (CVD) in systemic lupus erythematosus (SLE). Yet, how HDL is oxidized and rendered dysfunctional in SLE remains unclear. Neutrophil extracellular traps (NETs), which ar...

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Autori principali: Smith, Carolyne K., Vivekanandan-Giri, Anuradha, Tang, Chongren, Knight, Jason S., Mathew, Anna, Padilla, Robin L., Gillespie, Brenda W, Carmona-Rivera, Carmelo, Liu, Xiaodan, Subramanian, Venkataraman, Hasni, Sarfaraz, Thompson, Paul R., Heinecke, Jay W., Saran, Rajiv, Pennathur, Subramaniam, Kaplan, Mariana J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146708/
https://ncbi.nlm.nih.gov/pubmed/24838349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38703
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