Interleukin-21 Promotes Germinal Center Reaction by Skewing the Follicular Regulatory T Cell to Follicular Helper T Cell Balance in Autoimmune BXD2 Mice

OBJECTIVE: Follicular regulatory T (Tfr) cells act as the regulatory counterpart of follicular T helper (Tfh) cells to suppress germinal center (GC) B cell differentiation. We recently identified that interleukin 21 (IL-21) promoted Tfh differentiation in autoimmune BXD2 mice that develop spontaneou...

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Detaylı Bibliyografya
Asıl Yazarlar: Ding, Yanna, Li, Jun, Yang, PingAr, Luo, Bao, Wu, Qi, Zajac, Allan J., Wildner, Oliver, Hsu, Hui-Chen, Mountz, John D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146687/
https://ncbi.nlm.nih.gov/pubmed/24909430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38735
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