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Aging and alcohol interact to alter hepatic DNA hydroxymethylation

BACKGROUND: Aging and chronic alcohol consumption are both modifiers of DNA methylation but it is not yet known whether chronic alcohol consumption also alters DNA hydroxymethylation, a newly discovered epigenetic mark produced by oxidation of methylcytosine. Furthermore, it has not been tested whet...

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Main Authors: Tammen, Stephanie A., Dolnikowski, Gregory G., Ausman, Lynne M., Liu, Zhenhua, Sauer, Julia, SimonettaFriso, Choi, Sang-Woon
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146686/
https://ncbi.nlm.nih.gov/pubmed/25070523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.12477
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