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E2F1 is a novel fibrogenic gene that regulates cholestatic liver fibrosis through the Egr-1/SHP/EID1 network

E2F transcription factor 1 (E2F1) is an important regulator of metabolic diseases, however its role in liver function remains elusive. This study unraveled a regulatory cascade involving E2F1, early growth response-1 (Egr-1), nuclear receptor small heterodimer partner (SHP, NR0B2), and EIA-like inhi...

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Detalhes bibliográficos
Main Authors: Zhang, Yuxia, Xu, Ningyi, Xu, Jun, Kong, Bo, Copple, Bryan, Guo, Grace L., Wang, Li
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146672/
https://ncbi.nlm.nih.gov/pubmed/24619556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27121
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