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E2F1 is a novel fibrogenic gene that regulates cholestatic liver fibrosis through the Egr-1/SHP/EID1 network
E2F transcription factor 1 (E2F1) is an important regulator of metabolic diseases, however its role in liver function remains elusive. This study unraveled a regulatory cascade involving E2F1, early growth response-1 (Egr-1), nuclear receptor small heterodimer partner (SHP, NR0B2), and EIA-like inhi...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4146672/ https://ncbi.nlm.nih.gov/pubmed/24619556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27121 |
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