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A Critical Role for the mTORC2 Pathway in Lung Fibrosis
A characteristic of dysregulated wound healing in IPF is fibroblastic-mediated damage to lung epithelial cells within fibroblastic foci. In these foci, TGF-β and other growth factors activate fibroblasts that secrete growth factors and matrix regulatory proteins, which activate a fibrotic cascade. O...
Tallennettuna:
| Päätekijät: | , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Public Library of Science
2014
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4146613/ https://ncbi.nlm.nih.gov/pubmed/25162417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106155 |
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