Mineralocorticoid and AT(1) receptors in the paraventricular nucleus contribute to sympathetic hyperactivity and cardiac dysfunction in rats post myocardial infarct

Intracerebroventricular infusion of a mineralocorticoid receptor (MR) or angiotensin II type 1 receptor (AT(1)R) blocker in rats attenuates sympathetic hyperactivity and progressive left ventricular (LV) dysfunction post myocardial infarction (MI). The present study examined whether knockdown of MRs...

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Autores principales: Huang, Bing S, Chen, Aidong, Ahmad, Monir, Wang, Hong-Wei, Leenen, Frans H H
Formato: Artigo
Lenguaje:Inglês
Publicado: BlackWell Publishing Ltd 2014
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146375/
https://ncbi.nlm.nih.gov/pubmed/24951624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.276584
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