Faster cross-bridge detachment and increased tension cost in human hypertrophic cardiomyopathy with the R403Q MYH7 mutation

The first mutation associated with hypertrophic cardiomyopathy (HCM) is the R403Q mutation in the gene encoding β-myosin heavy chain (β-MyHC). R403Q locates in the globular head of myosin (S1), responsible for interaction with actin, and thus motor function of myosin. Increased cross-bridge relaxati...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Witjas-Paalberends, E Rosalie, Ferrara, Claudia, Scellini, Beatrice, Piroddi, Nicoletta, Montag, Judith, Tesi, Chiara, Stienen, Ger J M, Michels, Michelle, Ho, Carolyn Y, Kraft, Theresia, Poggesi, Corrado, van der Velden, Jolanda
Format: Artigo
Sprog:Inglês
Udgivet: BlackWell Publishing Ltd 2014
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146374/
https://ncbi.nlm.nih.gov/pubmed/24928957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.274571
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker