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Conditional site-specific recombination in mammalian cells using a ligand-dependent chimeric Cre recombinase.
We have developed a strategy to generate mutant genes in mammalian cells in a conditional manner by employing a fusion protein, Cre-ER, consisting of the loxP site-specific Cre recombinase linked to the ligand-binding domain of the human estrogen receptor. We have established homozygous retinoid X r...
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| Glavni autori: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
1995
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC41457/ https://ncbi.nlm.nih.gov/pubmed/7624356 |
| Oznake: |
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