Subsampled open-reference clustering creates consistent, comprehensive OTU definitions and scales to billions of sequences

We present a performance-optimized algorithm, subsampled open-reference OTU picking, for assigning marker gene (e.g., 16S rRNA) sequences generated on next-generation sequencing platforms to operational taxonomic units (OTUs) for microbial community analysis. This algorithm provides benefits over de...

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Hauptverfasser: Rideout, Jai Ram, He, Yan, Navas-Molina, Jose A., Walters, William A., Ursell, Luke K., Gibbons, Sean M., Chase, John, McDonald, Daniel, Gonzalez, Antonio, Robbins-Pianka, Adam, Clemente, Jose C., Gilbert, Jack A., Huse, Susan M., Zhou, Hong-Wei, Knight, Rob, Caporaso, J. Gregory
Format: Artigo
Sprache:Inglês
Veröffentlicht: PeerJ Inc. 2014
Schlagworte:
Bioinformatics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4145071/
https://ncbi.nlm.nih.gov/pubmed/25177538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.545
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