TGF-β upregulates CD70 expression and induces exhaustion of effector memory T cells in B-cell non-Hodgkin’s lymphoma

Transforming growth factor beta (TGF-β) plays an important role in mediating T-cell suppression in B-cell non-Hodgkin lymphoma (NHL). However, the underlying mechanism responsible for TGF-β-mediated inhibition of effector memory T (T(m)) cells is largely unknown. As reported here, we show that exhau...

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Autori principali: Yang, Zhi-Zhang, Grote, Deanna M., Xiu, Bing, Ziesmer, Steven C., Price-Troska, Tammy L., Hodge, Lucy S., Yates, Danielle M., Novak, Anne J., Ansell, Stephen M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4145058/
https://ncbi.nlm.nih.gov/pubmed/24569779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2014.84
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