Soluble and Membrane-Bound TGF-β-Mediated Regulation of Intratumoral T Cell Differentiation and Function in B-Cell Non-Hodgkin Lymphoma

While the effect of TGF-β on malignant B cells in non-Hodgkin lymphoma (NHL) has been previously evaluated, studies to specifically define the role of TGF-β in tumor immunity in B-cell NHL are limited. We found that soluble TGF-β, secreted by both lymphoma cells and intratumoral T cells, is present...

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Main Authors: Yang, Zhi-Zhang, Grote, Deanna M., Ziesmer, Steven C., Xiu, Bing, Yates, Nicole R., Secreto, Frank J., Hodge, Lucy S., Witzig, Thomas E., Novak, Anne J., Ansell, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3598706/
https://ncbi.nlm.nih.gov/pubmed/23555036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059456
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