Increased Presence of FOXP3(+) Regulatory T Cells in Inflamed Muscle of Patients with Active Juvenile Dermatomyositis Compared to Peripheral Blood

Juvenile dermatomyositis (JDM) is an immune-mediated inflammatory disease affecting the microvasculature of skin and muscle. CD4(+)CD25(+)FOXP3(+) regulatory T cells (Tregs) are key regulators of immune homeostasis. A role for Tregs in JDM pathogenesis has not yet been established. Here, we explored...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Vercoulen, Yvonne, Bellutti Enders, Felicitas, Meerding, Jenny, Plantinga, Maud, Elst, Elisabeth F., Varsani, Hemlata, van Schieveen, Christa, Bakker, Mette H., Klein, Mark, Scholman, Rianne C., Spliet, Wim, Ricotti, Valeria, Koenen, Hans J. P. M., de Weger, Roel A., Wedderburn, Lucy R., van Royen-Kerkhof, Annet, Prakken, Berent J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144849/
https://ncbi.nlm.nih.gov/pubmed/25157414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105353
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky