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Increased Presence of FOXP3(+) Regulatory T Cells in Inflamed Muscle of Patients with Active Juvenile Dermatomyositis Compared to Peripheral Blood
Juvenile dermatomyositis (JDM) is an immune-mediated inflammatory disease affecting the microvasculature of skin and muscle. CD4(+)CD25(+)FOXP3(+) regulatory T cells (Tregs) are key regulators of immune homeostasis. A role for Tregs in JDM pathogenesis has not yet been established. Here, we explored...
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| Autors principals: | , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4144849/ https://ncbi.nlm.nih.gov/pubmed/25157414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105353 |
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