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Interplay between regulatory T cells and PD-1 in modulating T cell exhaustion and viral control during chronic LCMV infection

Regulatory T (T reg) cells are critical for preventing autoimmunity mediated by self-reactive T cells, but their role in modulating immune responses during chronic viral infection is not well defined. To address this question and to investigate a role for T reg cells in exhaustion of virus-specific...

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Библиографические подробности
Главные авторы: Penaloza-MacMaster, Pablo, Kamphorst, Alice O., Wieland, Andreas, Araki, Koichi, Iyer, Smita S., West, Erin E., O’Mara, Leigh, Yang, Shu, Konieczny, Bogumila T., Sharpe, Arlene H., Freeman, Gordon J., Rudensky, Alexander Y., Ahmed, Rafi
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144726/
https://ncbi.nlm.nih.gov/pubmed/25113973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20132577
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