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Coupling of Transmembrane Helix Orientation To Membrane Release of the Juxtamembrane Region in FGFR3
[Image: see text] Activation of the protein tyrosine kinase receptors requires the coupling of ligand binding to a change in both the proximity and orientation of the single transmembrane (TM) helices of receptor monomers to allow transphosphorylation of the receptor kinase domain. We make use of pe...
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| Huvudupphovsmän: | , , , , , , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American
Chemical Society
2014
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| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4144707/ https://ncbi.nlm.nih.gov/pubmed/25010350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500327q |
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