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Coupling of Transmembrane Helix Orientation To Membrane Release of the Juxtamembrane Region in FGFR3
[Image: see text] Activation of the protein tyrosine kinase receptors requires the coupling of ligand binding to a change in both the proximity and orientation of the single transmembrane (TM) helices of receptor monomers to allow transphosphorylation of the receptor kinase domain. We make use of pe...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , |
|---|---|
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American
Chemical Society
2014
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| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4144707/ https://ncbi.nlm.nih.gov/pubmed/25010350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500327q |
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