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THE IMPACT OF OXYGEN TENSION ON CD8+ T CELL FUNCTION AND INTERACTION WITH GLIOMA CELLS

BACKGROUND: (blind field) METHODS: We studied a clonal population of gp100 antigen-specific CD8+ T cells from pmel-1 mice and the assays were performed in vitro in a hypoxia work station. 5% O2 corresponds to the expected oxygen fraction in lymph nodes where most T cells are physiologically primed....

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Detalhes bibliográficos
Main Authors: Walker, Paul R., de Silly, Romain Vuillefroy, Derouazi, Madiha
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144613/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou208.64
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