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IDENTIFYING DRUG COMPOUNDS TARGETING TUMOR METABOLISM IN GLIOBLASTOMAS
BACKGROUND: Rapidly proliferating tumour cells preferentially use aerobic glycolysis over oxidative phosphorylation (OXPHOS) to support growth and survive unfavorable microenvironment conditions. This metabolic reprogramming is referred to as the “Warburg effect”. We have shown that glycolytic enzym...
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| 第一著者: | |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4144579/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou208.33 |
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