STEM- AND PROGENITOR-LIKE CELL CONTRIBUTION TO MALIGNANT ASTROCYTOMA HETEROGENEITY

BACKGROUND: Stem-like tumor propagating cells (TPCs) isolated from malignant astrocytoma (MA) are reportedly therapy-resistant. In contrast, progenitor-like TPCs with loss of asymmetric cell division (Cancer Cell. 20:328-40; 2011) are sensitive to temozolomide (Cancer Cell. 18:669-82; 2010). In a pe...

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Detalhes bibliográficos
Main Authors: Petritsch, Claudia, Lerner, Robin, Lewis, Kate, Andor, Noemi, Ozawa, Tomoko, Yoshida, Yasuyuki, McMahon, Martin, Nicolaides, Theo, David James, C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144546/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou206.76
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