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Cell surface LAT is recruited to microclusters and is active in signaling

A controversy has recently emerged regarding the location of the cellular pool of the adapter LAT that participates in propagation of signals downstream of the T Cell Antigen Receptor (TCR). In one model phosphorylation and direct recruitment of cell surface LAT to activation-induced microclusters i...

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Autors principals: Balagopalan, Lakshmi, Barr, Valarie A., Kortum, Robert L., Park, Anna K., Samelson, Lawrence E.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144449/
https://ncbi.nlm.nih.gov/pubmed/23487428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202760
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