Propofol Inhibits Lipopolysaccharide-Induced Tumor Necrosis Factor-Alpha Expression and Myocardial Depression through Decreasing the Generation of Superoxide Anion in Cardiomyocytes

TNF-α has been shown to be a major factor responsible for myocardial depression in sepsis. The aim of this study was to investigate the effect of an anesthetic, propofol, on TNF-α expression in cardiomyocytes treated with LPS both in vivo and in vitro. In cultured cardiomyocytes, compared with contr...

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Autori principali: Tang, Jing, Hu, Ji-Jie, Lu, Chun-Hua, Liang, Jia-Ni, Xiao, Jin-Fang, Liu, You-Tan, Lin, Chun-Shui, Qin, Zai-Sheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144395/
https://ncbi.nlm.nih.gov/pubmed/25180066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/157376
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