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Propofol Inhibits Lipopolysaccharide-Induced Tumor Necrosis Factor-Alpha Expression and Myocardial Depression through Decreasing the Generation of Superoxide Anion in Cardiomyocytes

TNF-α has been shown to be a major factor responsible for myocardial depression in sepsis. The aim of this study was to investigate the effect of an anesthetic, propofol, on TNF-α expression in cardiomyocytes treated with LPS both in vivo and in vitro. In cultured cardiomyocytes, compared with contr...

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Hlavní autoři: Jing Tang, Ji-Jie Hu, Chun-Hua Lu, Jia-Ni Liang, Jin-Fang Xiao, You-Tan Liu, Chun-Shui Lin, Zai-Sheng Qin
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Limited 2014-01-01
Edice:Oxidative Medicine and Cellular Longevity
On-line přístup:http://dx.doi.org/10.1155/2014/157376
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