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Propofol Inhibits Lipopolysaccharide-Induced Tumor Necrosis Factor-Alpha Expression and Myocardial Depression through Decreasing the Generation of Superoxide Anion in Cardiomyocytes
TNF-α has been shown to be a major factor responsible for myocardial depression in sepsis. The aim of this study was to investigate the effect of an anesthetic, propofol, on TNF-α expression in cardiomyocytes treated with LPS both in vivo and in vitro. In cultured cardiomyocytes, compared with contr...
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Hlavní autoři: | , , , , , , , |
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Médium: | Artigo |
Jazyk: | Inglês |
Vydáno: |
Hindawi Limited
2014-01-01
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Edice: | Oxidative Medicine and Cellular Longevity |
On-line přístup: | http://dx.doi.org/10.1155/2014/157376 |
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