A Single, Acute Astragaloside IV Therapy Protects Cardiomyocyte Through Attenuating Superoxide Anion-Mediated Accumulation of Autophagosomes in Myocardial Ischemia-Reperfusion Injury

Myocardial ischemia-reperfusion (I/R) injury, characterized by myocardial cell death (e.g., apoptosis) and generation of reactive oxygen species (ROS) such as superoxide (O(2) (·−)) and hydrogen peroxide (H(2)O(2)), is a serious threat to human health and property. Saponin astragaloside IV (ASIV), e...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Huang, Kai-yu, Yu, Yong-wei, Liu, Shuai, Zhou, Ying-ying, Wang, Jin-sheng, Peng, Yang-pei, Ji, Kang-ting, Xue, Yang-jing
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8327213/
https://ncbi.nlm.nih.gov/pubmed/34349641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.642925
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