HIF-1α Signaling Activation by Post-Ischemia Treatment with Astragaloside IV Attenuates Myocardial Ischemia-Reperfusion Injury

In this study, we evaluated the effect of astragaloside IV (Ast IV) post-ischemia treatment on myocardial ischemia-reperfusion (IR) injury (IRI). We also examined whether hypoxia inducible factor-1α (HIF-1α) and its downstream gene-inducible nitric oxide (NO) synthase (iNOS) play roles in the cardio...

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Библиографические подробности
Главные авторы: Si, Jingwen, Wang, Ning, Wang, Huan, Xie, Juan, Yang, Jian, Yi, Hui, Shi, Zixuan, Ma, Jing, Wang, Wen, Yang, Lifang, Yu, Shiqiang, Li, Junchang
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2014
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169594/
https://ncbi.nlm.nih.gov/pubmed/25238237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107832
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