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Nrf2 Promotes the Development of Fibrosis and Tumorigenesis in Mice with Defective Hepatic Autophagy

BACKGROUND & AIMS: Autophagy is an intracellular lysosomal degradation process that plays an important role in regulating normal physiological functions of the liver. The purpose of the present study was to investigate the mechanism(s) by which the loss of hepatic autophagy leads to liver inflam...

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Detalhes bibliográficos
Main Authors: Ni, Hong-Min, Woolbright, Benjamin L., Williams, Jessica, Copple, Bryan, Cui, Wei, Luyendyk, James P., Jaeschke, Hartmut, Ding, Wen-Xing
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143992/
https://ncbi.nlm.nih.gov/pubmed/24815875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2014.04.043
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