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Choline kinase beta is required for normal endochondral bone formation
BACKGROUND: Choline kinase has three isoforms encoded by the genes Chka and Chkb. Inactivation of Chka in mice results in embryonic lethality, whereas Chkb(−/−) mice display neonatal forelimb bone deformations. METHODS: To understand the mechanisms underlying the bone deformations, we compared the b...
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4143985/ https://ncbi.nlm.nih.gov/pubmed/24637075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2014.03.008 |
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