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Antigen Potency and Maximal Efficacy Reveal a Mechanism of Efficient T Cell Activation

T cell activation, a critical event in adaptive immune responses, follows productive interactions between T cell receptors (TCRs) and antigens, in the form of peptide-bound major histocompatibility complexes (pMHCs) on the surfaces of antigen-presenting-cells. Upon activation, T cells can lyse infec...

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Detalhes bibliográficos
Main Authors: Dushek, Omer, Aleksic, Milos, Wheeler, Richard J., Zhang, Hao, Cordoba, Shaun-Paul, Peng, Yan-Chun, Chen, Ji-Li, Cerundolo, Vincenzo, Dong, Tao, Coombs, Daniel, van der Merwe, P. Anton
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143974/
https://ncbi.nlm.nih.gov/pubmed/21653229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2001430
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