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Systems Model of T Cell Receptor Proximal Signaling Reveals Emergent Ultrasensitivity
Receptor phosphorylation is thought to be tightly regulated because phosphorylated receptors initiate signaling cascades leading to cellular activation. The T cell antigen receptor (TCR) on the surface of T cells is phosphorylated by the kinase Lck and dephosphorylated by the phosphatase CD45 on mul...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3610635/ https://ncbi.nlm.nih.gov/pubmed/23555234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003004 |
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