RasGRP3 limits Toll-like receptor-triggered inflammatory response in macrophages by activating Rap1 small GTPase

Host immune cells can detect and destruct invading pathogens via pattern-recognition receptors. Small Rap GTPases act as conserved molecular switches coupling extracellular signals to various cellular responses, but their roles as regulators in Toll-like receptor (TLR) signalling have not been fully...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Tang, Songqing, Chen, Taoyong, Yu, Zhou, Zhu, Xuhui, Yang, Mingjin, Xie, Bin, Li, Nan, Cao, Xuetao, Wang, Jianli
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Pub. Group 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143924/
https://ncbi.nlm.nih.gov/pubmed/25118589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5657
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