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Non-covalent ligand conjugation to biotinylated DNA nanoparticles using TAT peptide genetically fused to monovalent streptavidin

DNA nanoparticles (DNA NPs), which self-assemble from DNA plasmids and poly-L-lysine (pLL)-polyethylene glycol (PEG) block copolymers, transfect several cell types in vitro and in vivo with minimal toxicity and immune response. To further enhance the gene transfer efficiency of DNA NP and control it...

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Detalles Bibliográficos
Main Authors: Sun, Wenchao, Fletcher, David, van Heeckeren, Rolf Christiaan, Davis, Pamela B.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143894/
https://ncbi.nlm.nih.gov/pubmed/22845840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/1061186X.2012.712128
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