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Monovalent Streptavidin that Senses Oligonucleotides
We report a straightforward chemical route to monovalent streptavidin, a valuable reagent for imaging. The one-step process is based on a (tris)biotinylated-oligonucleotide blocking three of streptavidin’s four biotin binding sites. Further, the complex is highly sensitive to single-base differences...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4109606/ https://ncbi.nlm.nih.gov/pubmed/23606329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201209948 |
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