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Comparison of several sequence-based association methods in pedigrees

Genome-wide association studies are very powerful in determining the genetic variants affecting complex diseases. Most of the available methods are very useful in detecting association between common variants and complex diseases. Recently, methods to detect rare variants in association with complex...

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Autori principali: Mathew, George, George, Varghese, Xu, Hongyan
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143807/
https://ncbi.nlm.nih.gov/pubmed/25519329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-8-S1-S48
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