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Simultaneous analysis of all single-nucleotide polymorphisms in genome-wide association study of rheumatoid arthritis

The availability of very large number of markers by modern technology makes genome-wide association studies very popular. The usual approach is to test single-nucleotide polymorphisms (SNPs) one at a time for association with disease status. However, it may not be possible to detect marginally signi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mathew, George, Xu, Hongyan, George, Varghese
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795881/
https://ncbi.nlm.nih.gov/pubmed/20017974
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