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Rare variant analysis of blood pressure phenotypes in the Genetic Analysis Workshop 18 whole genome sequencing data using sequence kernel association test

Sequence kernel association test (SKAT) has become one of the most commonly used nonburden tests for analyzing rare variants. Performance of burden tests depends on the weighting of rare and common variants when collapsing them in a genomic region. Using the systolic and diastolic blood pressure phe...

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Библиографические подробности
Главные авторы: Mallaney, Cates, Sung, Yun Ju
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143707/
https://ncbi.nlm.nih.gov/pubmed/25519353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-8-S1-S10
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