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Single-marker and multi-marker mixed models for polygenic score analysis in family-based data

Genome-wide association studies have proven successful but they remain underpowered for detecting variants of weaker effect. Alternative methods propose to test for association by using an aggregate score that combines the effects of the most associated variants. The set of variants that are to be a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bohossian, Nora, Saad, Mohamad, Legarra, Andrés, Martinez, Maria
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143662/
https://ncbi.nlm.nih.gov/pubmed/25519337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1753-6561-8-S1-S63
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